Previvors and Survivors
BRCA NEWSWORTHY
Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers. By the following:
Lim E, Vaillant F, Wu D, Forrest NC, Pal B, Hart AH, Asselin-Labat ML, Gyorki DE, Ward T, Partanen A, Feleppa F, Huschtscha LI, Thorne HJ; kConFab, Fox SB, Yan M, French JD, Brown MA, Smyth GK, Visvader JE, Lindeman GJ.
The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
Nat Med. 2009 Aug;15(8):907-13. Epub 2009 Aug 2. PMID: 19648928 [PubMed - in process]
Follow this link please: http://www.ncbi.nlm.nih.gov/pubmed/19648928
Researchers have found that breast tissue from BRCA1 positive women have large “luminal progenitor cells.” Originally it was thought that basal like breast cancers in BRCA1 positive women originated from the mammary stem cell, now it is being suggested that these cancers are from abnormal luminal progenitor cells.
When researchers find the reasons for cell changes causing breast cancer they will be able to target therapy cures to them.
BRCA NEWSWORTHY
New Cancer Vigilance reported by: Marilynne Marchione from The Associated Press. Follow this link: http://news.yahoo.com/s/ap/20090812/ap_on_he_me/us_med_breast_
cancer_lymph_nodes
It is being suggested that Breast Cancer patients with any lymph node involvement/early stage breast cancer – stray-microscopic cells may have a higher incidence of recurrent disease & may need more treatment than just surgery. Not all women are given estrogen blocking drugs & or chemo treatment. Some women have less aggressive breast cancer treatments—this is what is in question—should it be more aggressive?
BRCA NEWSWORTHY
From Study: Weightlifting helpful to breast cancer survivors reported by: Marilynn Marchione
Newsday.com. Follow this link: http://www.newsday.com/study-weightlifting-helps-breast-cancer-survivors-1.1365666
New research is coming out SUGGESTING to us that weight lifting may aid in the prevention of arm swelling rather than promoting it! They now suggest that lifting our groceries, weights etc. will help with muscle tone & not cause lymphadema— might even prevent it.
ALWAYS DISCUSS THESE THINGS WITH YOUR DOCTOR!!!
BRCA NEWSWORTHY
Prevent Cancer: Phase Out Toxics In Cosmetics And Personal Care Products reported by: WORLD-WIRE 7/20/09
Follow this link for this very important article: http://world-wire.com/news/0907150002.html
BRCA NEWSWORTHY
Breast Cancer Treatment Without Surgery reported by Dr. Sapna Parikh from myfoxny.com 7/14/09
Follow this link: http://www.myfoxny.com/dpp/good_day_ny/090714_
Breast_Cancer_Treatment_Without_Surgery
It’s a new national clinical study going on right now & it’s called “cryoablation.” Dr. Simmons from the Iris Cantor Women’s Health Center in NYC was interviewed. It’s a 20 minute procedure that freezes & kills the breast cancer cells. It can be done in the doctor’s office & can possibly eliminate the need for chemotherapy in the future. It’s possible that the side effect of this technique can boost the patient’s own body to fight off its own cancer in the future!
BRCA NEWSWORTHY
Metabolic Syndrome May Make Breast Cancer More Likely from Health Day by Robert Preidt 6/30/09 (source: American Association for Cancer Research)
Follow this link: http://www.nlm.nih.gov/medlineplus/news/fullstory_86263.html
Women with Metabolic Syndrome (insulin resistance syndrome) or women having some form of the syndrome have an increased risk of post menopausal breast cancer.
Women with Metabolic syndrome usually have abnormal glucose levels, high blood pressure, abdominal obesity, usually poor diets & little exercise.
BRCA NEWSWORTHY
Followup: Antiperspirants and Cancer by CBS News investigative reporter Sharyl Attkisson 6/29/09 follow this link:
http://www.cbsnews.com/stories/2009/06/29/cbsnews_
investigates/main5123621.shtml
The FDA, CDC, NIH & the antiperspirant people will not rule out a link between the products that contain aluminum & breast cancer risk, but they also tell us not to throw away our products. Apparently nothing has changed…deodorants are so called safer products but they only mask odor- they don’t keep you from sweating.
(since this is my blog…I can let you know that Toms of Maine has an aluminum free deodorant!)
BRCA NEWSWORTHY
If you would like to hear Jessica Queller’s interview go here:
BRCA NEWSWORTHY
New drug olaparib offers hope to women with genetic breast cancer by David Rose
Follow this link: http://www.timesonline.co.uk/tol/life_and_style/health/article6400852.ece
Olaparib is made by AstraZeneca & is being used in clinical trials to treat & or prevent cancer in high risk or BRCA families. They feel this drug is very promising in blocking the protein that makes cancer cells –causing only the cancer cell to either die or shrink. (BRCA patients have the mutated gene that is supposed to repair or fix damaged DNA—therefore when the repair doesn’t work properly mistakes in the DNA accumulate, do not repair & cancer develops.)
BRCA NEWSWORTHY
Antidepressants cut effectiveness of Tamoxifen in Breast Cancer by Lisa Rapaport
Please follow this link for the entire article: http://www.bloomberg.com/apps/news?pid=20601103&sid=acVRDiRcYWzQ&refer=news
I found this article worthy of passing on to you readers…ALWAYS DISCUSS ANY OF THESE THINGS WITH YOUR PHYSICIAN!
A study says…Prozac, Zoloft, Paxil when taken with Tamoxifen was more likely to inhibit the effectiveness of taking Tamoxifin therefore…increases the risk of your tumor returning when compared to women who didn’t take the above mentioned antidepressants. These antidepressants are known as SSRI’s (selective serotonin reuptake inhibitors) & they use the same supply of enzymes (found in our liver) to make them effective that Tamoxifin uses—therefore they have to share the supply of enzymes making Tamoxifin weaker. SSRI’s also include the medications Celexa & Lexipro- but Paxil was found in the study to be the strongest in blocking the enzyme.
Effexor was mentioned as not interfering with the effects of Tamoxifen.